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Gut Health: Why Your Microbiome Matters

Your gut microbiome contains trillions of beneficial bacteria that influence many aspects of health. These microorganisms support digestion, regulate the immune system, and play an important role in skin health, mood, hormones and metabolism.

When the microbiome is balanced, the body can function at its best — but disruptions can affect many areas of wellbeing. For founder Hanna Sillitoe, understanding the connection between gut health and the body was life-changing. After years of struggling with severe psoriasis, she discovered how supporting the gut microbiome could play a powerful role in improving skin and overall health.

Gut & Skin

Gut & Digestion

Gut & Digestion

Gut & Hormones

Gut & Immunity

Gut & Mood

Gut & Metabolism

Probiotics

Liquid supplement

100% natural

15 bio-live cultures

No added sugar or sweeteners

Hand-brewed in the UK

Added vitamins and botanicals

No preservatives or fillers

Certified gluten free

Vegan society approved

Sustainably packaged

How to Improve Gut Health

Small changes in diet and lifestyle can have a powerful impact on the health and balance of your gut microbiome.

Eat diverse plant foods

A varied plant-based diet helps feed beneficial gut bacteria.

Increase daily fibre intake

Fibre supports digestion and helps nourish the microbiome.

Fermented foods

Sauerkraut, kefir and kimchi naturally contain beneficial bacteria.

Take a liquid probiotic

Live cultures can help support beneficial gut microbes.

Prioritise good sleep

Sleep plays an important role in gut health and overall wellbeing.

The Gut–Hormone Axis: How Your Microbiome Influences Hormones

Hormones play an essential role in regulating many processes in the body, including metabolism, mood, reproduction and energy levels. While hormones are produced by glands within the endocrine system, growing research suggests that the gut microbiome may also influence hormone regulation.

Scientists are increasingly exploring the relationship between gut bacteria, inflammation and hormone metabolism. This interaction between the gut microbiome and the endocrine system is often referred to as the gut–hormone axis.

Understanding this connection may help explain how supporting gut health could influence hormonal balance and overall wellbeing.

Hanna Sillitoe first became interested in the connection between gut health and the wider body while recovering from severe psoriasis. During this time she began exploring research into the microbiome and its influence on inflammation, immunity and overall health.

This experience sparked a long-standing interest in the role of the gut microbiome in regulating processes throughout the body, including hormonal balance.




The gut–hormone axis describes the relationship between the gut microbiome and the endocrine system, which produces and regulates hormones.

The gut microbiome is made up of trillions of microorganisms that live within the digestive system. These microbes interact with many systems throughout the body, including immune cells, metabolic pathways and hormone signalling.

Researchers have discovered that certain gut bacteria can influence how hormones are produced, metabolised and recycled within the body.

Because hormones regulate many essential functions, scientists are increasingly exploring how microbiome balance may influence hormonal health.




Microbiome and hormone metabolism

Certain gut bacteria help break down and metabolise hormones within the digestive system. This process can influence how hormones circulate within the body.

The estrobolome

One important group of gut bacteria known as the estrobolome plays a role in metabolising oestrogen. These microbes influence how oestrogen is processed and recycled within the body.

Immune regulation

The microbiome interacts closely with immune cells, helping regulate inflammation throughout the body. Because inflammation can influence hormonal signalling, microbiome balance may affect hormone regulation.

Metabolic signalling

Gut microbes also influence metabolic pathways involved in insulin sensitivity, appetite regulation and energy balance.

Interest in the gut–hormone axis has grown significantly in recent years.

Research suggests:

• Gut bacteria may influence how hormones are metabolised and recycled in the body
• Microbiome diversity may play a role in metabolic and hormonal balance
• Certain microbes influence oestrogen metabolism through the estrobolome
• Inflammation linked to microbiome imbalance may influence hormone signalling

Although research is still developing, these findings highlight the growing interest in how microbiome balance may influence hormonal health.

Healthy microbiome diversity may support many systems throughout the body.

Eat diverse plant foods

Plant diversity helps nourish beneficial gut bacteria.

Increase fibre intake

Fibre provides fuel for microbes that produce beneficial compounds.

Include fermented foods

Fermented foods contain naturally occurring microorganisms.

Maintain healthy lifestyle habits

Sleep, stress levels and exercise all influence microbiome balance.

Consider probiotic support

Some people choose probiotics to help support microbiome diversity.




Can gut health affect hormones?
Emerging research suggests the microbiome may influence hormone metabolism and immune regulation.

What is the estrobolome?
The estrobolome refers to gut bacteria involved in oestrogen metabolism.

Can probiotics affect hormones?
Scientists are investigating how probiotics may influence microbiome balance and hormone signalling.

The relationship between the microbiome and hormonal health is an exciting and rapidly developing area of research. Scientists are increasingly exploring how gut bacteria may influence hormone metabolism, inflammation and immune signalling.

Supporting a healthy and diverse microbiome may therefore play a role in maintaining overall hormonal balance and wellbeing.

Some people choose to support their microbiome with probiotics — live cultures designed to help maintain a healthy balance of gut bacteria.

WHY DO PROBIOTICS MATTER?

“Modern diets often lack the bacteria and vitamins we need to support our internal ecosystem, which is where taking a multi strain probiotic supplement can really help.”

Hanna Sillitoe

Founder + Formulator

Understanding the Estrobolome: How Gut Bacteria Influence Oestrogen

Hormones regulate many essential processes throughout the body, including metabolism, reproduction, mood and skin health. One hormone that plays a particularly important role in women’s health is oestrogen.

In recent years, scientists have discovered that certain bacteria within the gut microbiome influence how oestrogen is metabolised and recycled in the body. These bacteria form what researchers call the estrobolome.

Understanding the estrobolome is helping researchers explore how the gut microbiome may influence hormonal balance, inflammation and overall health.

Hanna Sillitoe first became interested in the connection between gut health and the wider body while exploring natural treatments for her chronic skin complaints. During this time she began exploring research into the gut microbiome and its influence on inflammation and immune responses.

This journey led to a deeper interest in how the microbiome influences many systems throughout the body, including hormone regulation and metabolic health.

The estrobolome refers to a group of gut bacteria capable of metabolising oestrogen within the digestive system.

After oestrogen is produced by the body, it is processed by the liver and released into the digestive tract. At this stage, certain gut bacteria produce enzymes that determine whether oestrogen is:

  • broken down and excreted
  • reabsorbed into circulation

This means that gut microbes help regulate how much oestrogen continues circulating in the body.

Because oestrogen plays an important role in many systems — including bone health, skin health, metabolism and cardiovascular function — researchers are increasingly interested in how the estrobolome may influence hormonal balance.

The Gut–Hormone Axis

The gut–hormone axis describes the interaction between the gut microbiome and the endocrine system.

The gut microbiome contains trillions of microbes that interact closely with immune cells, metabolic pathways and hormone signalling throughout the body.

Oestrogen metabolism

Certain bacteria in the estrobolome produce an enzyme called beta-glucuronidase, which helps break down oestrogen compounds within the digestive tract.

This process determines whether oestrogen is excreted from the body or reabsorbed into the bloodstream.

Microbiome diversity

A diverse microbiome generally contains a wide range of beneficial bacterial species. Reduced microbial diversity may influence how effectively the estrobolome functions.

Inflammation and hormone balance

Because the microbiome helps regulate immune responses, imbalances in gut bacteria may influence inflammatory pathways that interact with hormone signalling.

Interest in the estrobolome has grown rapidly in recent years as scientists explore how gut microbes influence hormone metabolism.

Research findings include:

• Microbiome influence on oestrogen metabolism – Studies have identified specific gut bacteria capable of metabolising oestrogen within the digestive system.

• The estrobolome and hormone circulation – Research suggests that gut bacteria influence how oestrogen is recycled within the body.

• Microbiome diversity and hormone balance – Reduced microbiome diversity may influence oestrogen metabolism and hormone signalling.

• Links to metabolic and inflammatory health – Because oestrogen interacts with immune and metabolic pathways, the estrobolome may influence broader aspects of health.

Although research into the estrobolome is still developing, these findings highlight the growing scientific interest in how gut bacteria may influence hormone regulation.

aintaining a healthy and diverse microbiome may help support many systems in the body, including hormone metabolism.

Eat a diverse range of plant foods

Plant diversity provides fibre and nutrients that nourish beneficial gut bacteria.

Increase fibre intake

Fibre helps fuel gut microbes that produce compounds important for gut barrier function and immune balance.

Include fermented foods

Fermented foods such as sauerkraut, kimchi and kefir contain naturally occurring microorganisms that may support microbiome diversity.

Maintain healthy lifestyle habits

Sleep, physical activity and stress management can influence microbiome balance and metabolic health.

Consider probiotic support

Some people choose probiotics to help support microbiome diversity and maintain a balanced gut environment.

What is the estrobolome?

The estrobolome refers to gut bacteria involved in metabolising oestrogen within the digestive system.

Why is the estrobolome important?

Because it influences how oestrogen is processed and recycled in the body, potentially affecting hormone balance.

Can gut health affect oestrogen levels?

Emerging research suggests the gut microbiome may influence how oestrogen circulates in the body through its role in hormone metabolism.

The discovery of the estrobolome highlights the complex relationship between the gut microbiome and hormone regulation. Scientists are increasingly exploring how gut bacteria influence the metabolism and circulation of oestrogen within the body.

Although research is still developing, maintaining a healthy and diverse microbiome may play an important role in supporting hormonal balance and overall wellbeing.

Understanding the connection between gut bacteria and hormone metabolism offers new insights into how internal systems interact to influence health.

Some people choose to support their microbiome with probiotics — live cultures designed to help maintain a healthy balance of gut bacteria.

FAQs

Our Multi Strain Biotic is safe for children and can offer various health benefits. The recommended dosages are as follows:

  • 5 drops once a day for children under 7 years of age
  • One teaspoon for children aged 7 and older

It is best consumed on an empty stomach, first thing in the morning, to optimise results. For infants, it can be added to formula or directly onto the nipple during breastfeeding. In any case, if there's ever a hesitation, it's best to consult with a physician familiar with the child's health.

The Multi Strain Biotic is considered safe to consume during pregnancy and also while breastfeeding. It has been used by many, including our founder, throughout her pregnancy and continued use during breastfeeding. It's always recommended to speak with your GP or midwife if you have any doubts or questions, as they are familiar with you and your medical history.

If you're looking for shared experiences or additional information, we have a blog post that discusses skin flare-ups during and after pregnancy.

Our Multi Strain Biotic is a naturally brewed product, and because of this, you may notice differences in taste or texture between different batches. Variations such as fizziness when opening or tasting, or the presence of cloudiness or particles in the liquid, are quite normal and do not impact the efficacy of the product. We liken the taste to sour apple juice and assure you that these characteristics are natural and expected.

Our Multi Strain Biotic has a best before date printed on the packaging. Once opened, it should ideally be consumed within 2 months to maintain its quality and effectiveness. Be sure to store it as directed to ensure the product remains at its best during its shelf life.

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